16mm film combined catalog (1972)

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1966-67 NEW FILMS 91 City. Available for loan (free) from the USAEC headquarters and field libraries nationwide. Cleared for educational television. This film, made at AEC's Brookhaven National Labora- tory, shows how blood and/or lymph may be irradiated in a well-shielded gamma ray source outside of the body through a closed circuit of teflon tubes from artery to vein. New surgical techniques and plastic methodology have made this tool available for extensive research in experimental animals as well as in human beings. The basic principle concerns the relative radiation resistance of erythrocytes (red blood cells) and the radiation sensi- tivity of the normal white cells (lymphocytes). The tech- nique, known as extracorporeal irradiation, is still experi- mental. It may prove to be of some therapeutic value to patients with leukemia and severe kidney disease. Surgeons working in the operating room section of the experimental animal barn are shown fitting a calf with an external loop of teflon linking the carotid artery to a vein. The loop may be enlarged to include a cobalt-60 or a cesium-137 irradiation source. Before the irradiator is added to the loop, the animals are injected with heparin to prevent clotting of the blood during its flow past the source and back into the animal. A similar method for irradiation of lymph fluid outside the body employs an external plastic loop from thoracic lymphatic organs to a vein. The lymphocytes—an integral part of the foreign tissue rejection mechanism—may be depleted by extracorporeal irradiation, thus interfering with the normal body reaction of rejection of transfused blood, skin grafts, or organ transplants, etc. The final scenes show a human patient with chronic mylocytic leu- kemia receiving treatment. RETURN TO BIKINI (1966). 23% minutes, color. Produced for the AEC by the Laboratory of Radia- tion Biology, University of Washington. For sale by the Motion Picture Service, U. S. Department of Agriculture, Washington, D. C. 20250, at $97.00 per print, including shipping case. Available for loan (free) from the USAEC headquarters and field li- braries. Cleared for television. Describes the latest scientific survey by a team from the Laboratory of Radiation Biology of the University of Washington to determine the condition of Bikini and Eni-