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62 UNDERSTANDING THE ATOM SERIES This film traces the development of the use of radioisotopes and radia- tion in the field of medicine from the early work by Hevesy to the pres- ent. The program is presented by Dr. John Cooper of Northwestern University, who is introduced by Dr. Ralph T. Overman, Chairman, Special Training Division of the USAEC's Oak Ridge Institute of Nu- clear Studies and regular lecturer of the series. Dr. Cooper's discus- sion includes the area of medical research, diagnosis and therapy. The source of cholesterol in the human body and the applications of this basic information to clinical studies of atherosclerosis is described. Similarly, studies with cobalt-labeled vitamin B-12, used to study pernicious anemia, are also discussed. Most of the information now known about thyroid physiology and pathology has been determined with the aid of various iodine radioisotopes, and standard diagnostic mea- surements and scanning are described in the film. Brain tumor local- ization is also covered. A very important area of radioisotope use is the determination of a variety of body fluid volumes such as blood and plasma. Red cell volume and lifetime can also be measured using labeled cells. The film explains how radioisotopes are used for the treatment of various diseases, including hyperthyroidism and cancer. RADIOISOTOPES IN BIOLOGY AND AGRICULTURE (1964). 26 min- utes. Produced by the Educational Broadcasting Corporation, New York City, under the joint direction of USAEC's Divisions of Isotope Development and Nuclear Education and Training, and the Oak Ridge Institute of Nuclear Studies. For sale by Bryon Motion Pictures, at $32.54 per print, including shipping case, F.O.B. Washington, D. C. This film is a lecture by Dr. Howard Curtis of Brookhaven National Laboratory, who is introduced by Dr. Ralph T. Overman, Chairman, Special Training Division of the USAEC's Oak Ridge Institute of Nu- clear Studies and regular lecturer of the series. Dr. Curtis touches on some of the up-to-date applications of atomic energy to biology and agriculture. Reference is made to the importance of radioisotopic tracers in the determination of the structure and role of nucleic acids and other cellular components. This work is done either with various types of counters or autoradiography. For example, the position of DNA in the cell has been determined quite specifically. This informa- tion has been exceedingly important in the breaking of the genetic code by determining the area of the sub units on the backbone of the geneti- cally important molecules. Similarly, the structure of proteins has been determined using radioactive tracers. In addition to tracer appli- cations, a great deal of information has been gained by studying radia- tion effects. This has been important both from the standpoint of fun- damental knowledge about growth and also the practical applications of economically important mutations. Interesting examples of plantbreed-