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page 7 hemocyanin, in their Mood in place of the iron compound, hemo¬ globin, that is jjresent in most animals today# The animals that have the iron compound hemoglobin circulating in their blood, still mast rely on the evolutionary progenitor, copper for the synthesis of hemoglobin# In support of this theory of the evolutionary significance of copper in nutrition ojf//// is the fact that the copper content of the taeriybody is greatesfin Infancy and prenatal life and is least in the adult# The/ best food sources of copper are liver, oysters, cocoa, nuts, currants and. peas. Iodine is a absolute essential in the dietary although the daily requirement is small, 1/600,000 of an oz# In regions where the water and the soil are deficientjln iodine, goiter is prevalent as in tae great lakes States in this country and in Switzerland# Inorganic iodine compounds are well utilized so that t ie introduction of // iodized salt has very greatly deci*easod the incidence of goiter in this country# The need for iodine is a further example of our depen¬ dence on the sea and //// the inheritance through 400,000,000 years of that dependence# The ocean is the great source of iodine, in fact iodine was formerly extracted in commercial quantities from sea weed In our searca for dietary iodine, we are led back to the ocean that cradled our primordial ancestors, fish and oysters being the best food sources# The iodine content of vegetables is dependent on the iodine b content of the soil in walca the vegetales grow, so that a general statement of the food iodine content of these vegetables is not poss¬ ible# Hart and klv^Jem at Wisconsin in 1931 demonstrated the importance of manganese in taint aiming the mm normal reproductive cycle in expemental rats, but t.kLs element is required in such minute amounts and is so widely distributed in plant foods, thaljit cannot become a Uni¬ ting factor in human nutrition#